Mefenamic Acid – Key Facts & Practical Guides

When working with Mefenamic Acid, a non‑steroidal anti‑inflammatory drug (NSAID) used for short‑term pain relief. Also known as Ponstel, it blocks cyclooxygenase enzymes to lower inflammation and fever. NSAIDs, a drug class that reduces pain, inflammation, and fever by inhibiting cyclooxygenase share this core mechanism. This means Mefenamic Acid is a type of NSAID, NSAIDs inhibit cyclooxygenase enzymes, cyclooxygenase inhibition reduces prostaglandin production, and reduced prostaglandins lower inflammation and pain. Because the pathway touches the stomach lining and kidney function, patients with ulcer history or renal impairment should think twice before starting therapy.

How It Fits Into Pain Management and Safety Planning

The primary attribute of Mefenamic Acid is its ability to manage acute musculoskeletal pain, dental pain, and menstrual cramps. It works best for short courses – typically not more than 7 days – to avoid cumulative side effects. A related entity, drug interactions, situations where one medication affects the safety or effectiveness of another, is critical: combining Mefenamic Acid with anticoagulants, other NSAIDs, or selective serotonin reuptake inhibitors can raise bleeding risk. Pregnancy adds another layer; the drug falls into category C, meaning risks cannot be ruled out, so clinicians usually recommend alternatives for expectant mothers. Gastro‑intestinal protection is another concern; using a proton‑pump inhibitor or an H2 blocker alongside Mefenamic Acid can help shield the stomach lining, especially for older adults or anyone with a history of ulcers.

Below you’ll find a curated set of articles that dive deeper into these topics. We’ve gathered guides on safe online purchasing of generic NSAIDs, side‑by‑side comparisons of common pain relievers, and checklists for spotting drug‑interaction red flags. Whether you’re looking for a cost‑effective way to get Mefenamic Acid, want to understand how it stacks up against other NSAIDs, or need advice on managing side effects, the posts below provide practical, easy‑to‑follow information that can help you make informed decisions.